The carboxylic acid group of quinolones was modified; so, we designed new quinolones derivatives with different antioxidants using Ligand Designer from Glide (Schrodinger LLC).The cap group and the linker were optimized through trying various aliphatic and aromatic residues.A new synthesized derivatives (IIa-Vb) were synthesized by esterification o

This paper deals with the joint subcarrier and power allocation problem in a downlink multi-user orthogonal frequency division multiplexing system subject to user delay and minimum rate quality-of-service (QoS) requirements over a frequency-selective multi-copyright fading channel.We aim to maximize the utility-pricing function, formulated as the d

Joseph T Krill, Rishi D Naik, Michael F Vaezi Division of Gastroenterology, Hepatology, and Nutrition, Center for Swallowing and Esophageal Disorders, Vanderbilt University Medical Center, Nashville, TN, USA Abstract: Achalasia is a primary disorder of esophageal motility.It classically presents with dysphagia to both solids and liquids but may be

This study evaluates the possible effects of sawdust from scrap wood on the mechanical and microstructure characteristics of interlocking bricks when used as an additive in construction materials.Bricks with increased porosity levels were manufactured by adding Wipes more recycled wood sawdust ash (WSA) additive at larger sizes.The findings demonst

Contradictory scaling behavior in experiments testing the principle of universality may be due to external oscillations.Thus, the effect of damped oscillatory external forces on slip avalanches in slowly deformed solids is simulated using Electronics a mean-field model.Akin to a resonance effect, oscillatory driving forces change the dynamics of av